I got up and running without reading any directions, and I am not some super techy guy. We hooked up 3 people, and it all went great. The only thing you need to guard against is an attendee having their volume too high and creating a repeat like loop. Just don't have speakers pointing at the computer.
The white boards were awesome, you can create a bunch of them if you want to. Sharing the computer screen was easy. The design of this is superb. This is really worthwhile to have even just for personal use. Get 5 of your friends together and have a virtual party, you can even record it! We are using it to stream Christmas to our family and have a more reliable meet up space than Facebook. This will be a great business tool. You can log back in and all the white boards are still there. This could be used for You Tube videos too, as you can record say an interview and then download the video, and upload it to You Tube.