I've been using Wonders' free plan for months now and never thought I'd have the chance to grab a lifetime plan for such a low price.

If you haven't tried Wonders yet and you're still on the fence on if you should get this or not - let me just tell you that you absolutely should. Wonders completely changed how I approach research not only professionally, but personally - it's my go to first stop whenever I'm exploring a new topic on literally anything.

One of the most profound experiences I've had using the site is when my partner and I were expecting a child and unfortunately realized that our child had a profoundly rare fatal bone disorder, hypophosphatasia. The disease is so rare that pretty much no one ever has heard of it, and we realized that both of us were potentially not only carriers, but quite likely had subclinical cases of hypophosphatasia ourselves - and of course we went through a massive deep dive of the literature using Wonders, which profoundly helped us narrow down exactly what we needed to find and know in a subject area neither of us had familiarity in.

The suggested topic search feature is incredible, and helps me explore both research areas I'm an expert in and those where I have basically no preexisting knowledge of in far greater depth and infinitely more quickly than I could myself. Some examples from this particular case:

From just inputting my basic search:
Hypophosphatasia pathogenic variant c.346G>A (p.A116T) in the ALPL gene

Wonders immediately suggested the following areas for me to branch off into:

1. Investigate enzymatic dysfunction in ALPL gene c.346G>A (p.A116T) with kinetic assays.

2. Explore impact of c.346G>A (p.A116T) on bone mineralization using advanced imaging.

3. Analyze ALP protein misfolding due to c.346G>A (p.A116T) mutation.

4. Compare clinical manifestations of c.346G>A (p.A116T) with other ALPL variants.

5. Examine c.346G>A (p.A116T) using molecular dynamics simulations.

6. Synthesize genetic counseling protocols for c.346G>A (p.A116T) carriers.

7. Review epidemiological trends of c.346G>A (p.A116T) globally.

8. Evaluate therapeutic targets for c.346G>A (p.A116T) through pathway analysis.

9. Study allele-specific expression patterns in c.346G>A (p.A116T) carriers.

All of which were exactly the kinds of things I was looking to dive into more deeply but had no idea how to express myself.

The only thing I've been missing on my free plan has been enough searches to properly explore all the subjects I've been wanting to dive into in proper depth - but this deal solves all of that for me, for life :)

If you're still reading this you really should be buying Wonders instead.